Research
Experience as Investigator
| S. No. | Title of Project | Role | Funding Agency | Amount(₹) | Reference of Main Publications |
| 1 | High molecular weight (HMW) HLA-B27 aggregates and Ankylosing Spondylitis (AS) | PI | DBT | 87,24,000.00 | Int Immunopharmacol. 2022 Nov;112:109226.Front Immunol. 2022 Jan 10;12:795053. |
| 2 | Understanding the association of ankylosing spondylitis (AS) with misfolding of HLA B27 | PI | DBT | 30,95,000.00 | FEBS Lett. 2004 Sep 24;575(1-3):1-8.Biochim Biophys Acta. 2007 Dec;1772(11-12):1258-69. |
| 3 | Establishment of DNA based HLA typing laboratory at PGIMER, Chandigarh | PI | DBT | 51,71,000.00 |
Immunol Invest. 2012;41(2):117-28.Biochim Biophys Acta. 2009 Oct;1790(10):1282-94. |
| 4 | Modulation of activity of MMPs in the ECM surrounding RPE cells from PVR patients | PI | DST | 32,00,000.00 |
Enzyme Microb Technol. 2021 Jun;147:109779. |
| 5 | Evaluation of Platelet Activation and GPIIb/IIIa Conformational Status in ITP | PI | DBT | 38,98,000.00 |
Platelets. 2015;26(2):119-26.MAbs. 2015;7(6):1212-20. |
| 6 | Molecular and morphological monitoring of neuronal transdifferentiation of RPE cells by growth factors | PI | DST | 35,00,000.00 | Curr Eye Res. 2011 May;36(5):469-80.Curr Eye Res. 2012 Jul;37(7):606-16. |
| 7 | Protein engineering strategies to target posterior capsular opacification | PI | CSIR | 21,00,000.00 | Sci Rep. 2016 Aug 3;6:30872.Invest Ophthalmol Vis Sci. 2014 Dec 1;55(13):8394-402. |
Research Projects
1. Title: Examination of structural aspects of the intermolecular interactions among crystallins in the lens
Funding Agency: ICMR
Funding Amount: ₹9.03 lakhs
Duration: June 2005 – June 2008
2. Title: Establishment of DNA based HLA typing laboratory at PGIMER, Chandigarh
Funding Agency: DBT
Funding Amount: ₹51.71 lakhs
Duration: February 2006 – February 2009
3. Title: Understanding the association of ankylosing spondylitis (AS) with misfolding of HLA B27
Funding Agency: DBT
Funding Amount: ₹30.95 lakhs
Duration: August 2007
4. Title: Modulation of activity of matrix metalloproteases (MMPs) in the extracellular matrix surrounding cultured retinal pigment epithelial (RPE) cells derived from proliferative vitreoretinopathy (PVR) patients
Funding Agency: DST
Funding Amount: ₹32 lakhs
Duration: February 2007 – February 2010
5. Title: An Evaluation of Platelet Activation and GPIIb/IIIa Conformational Status in ITP
Funding Agency: DBT
Funding Amount: ₹38.98 lakhs
Duration: September 2009 – September 2012
6. Title: Molecular and morphological monitoring of neuronal transdifferentiation of retinal pigment epithelial cells in culture system by combinations of growth factors
Funding Agency: DST
Funding Amount: ₹35.0 lakhs
Duration: October 2009 – 2012
7. Title: Protein engineering-based strategies to target posterior capsular opacification
Funding Agency: CSIR
Funding Amount: ₹21.0 lakhs
Duration: November 2010 – 2013
8. Title: Exploration of conformational issues in HLA-B27 misfolding
Funding Agency: DBT
Funding Amount: ₹43.32 lakhs
Duration: 2012 – 2015
9. Title: Exploring the efficacy of targeting ECM components relevant to rheumatoid arthritis
Funding Agency: DBT
Funding Amount: ₹34.17 lakhs
Duration: 2012 – 2015
10. Title: Testing reagents designed to re-organize the extracellular matrix and vitreous in the human eye
Funding Agency: ICMR
Funding Amount: ₹60.0 lakhs
Duration: 2015 – 2018
11. Title: Proliferative vitreoretinopathy: pathophysiology and pharmacotherapeutics
Funding Agency: SERB
Funding Amount: ₹57.6 lakhs
Duration: 2016 – 2019
12. Title: High molecular weight (HMW) HLA-B27 aggregates and Ankylosing Spondylitis (AS)
Funding Agency: DBT
Funding Amount: ₹87.24 lakhs
Duration: 2019 – 2022